Politics

/

ArcaMax

Editorial: This potential pancreatic cancer treatment breakthrough should be celebrated

Chicago Tribune Editorial Board, Chicago Tribune on

Published in Op Eds

Our fraught national debate over immunization and public health has overshadowed some extremely encouraging advances being made by researchers in the decades-long battle against cancer.

Recent news of a potential breakthrough vaccine for one of the most lethal of all cancers — pancreatic cancer — demonstrates why continued federal research support for such treatments remains so vital.

Once diagnosed, pancreatic cancer has been a death sentence for those afflicted in the vast majority of cases. With conventional treatments, just 13% of patients are alive five years after diagnosis, according to the American Cancer Society.

Recently disclosed results of the test of an experimental vaccine using messenger RNA (mRNA) on 16 patients were extraordinarily positive. The immune systems of eight of the 16 in the trial responded to the vaccine. Of those eight, seven were alive four to six years after surgery, according to Memorial Sloan Kettering Cancer Center in New York, which performed the study.

Of the eight patients whose systems didn’t respond, just two have survived to this point. The six who died survived a median of 3.4 years.

Obviously, this is a very small sample. A larger group is being tested in a second phase of clinical trials. This vaccine also is only for patients whose tumors are operable. Those diagnosed at later stages — such as former U.S. Sen. Ben Sasse, who has spoken openly and movingly about his experience — can’t currently benefit from this technology.

But this study is a real ray of hope for treating a disease that is the third leading cause of cancer deaths in the U.S. and essentially doesn’t respond to ordinary cancer treatments like chemotherapy and radiation.

 

The mRNA technology involves producing individualized vaccines, developed after patients have their pancreatic tumors removed and analyzed. When the vaccines work, the patient’s body is trained to produce so-called T cells that kill the cancer cells along with another kind of T cell that helps sustain the immune response.

“As we continue to learn more about how these vaccines work, there is a real belief and determination in the pancreatic cancer community that we can effectively treat this disease by training the patient’s own immune system,” said Dr. Vinod Balachandran, who led the trial and is Memorial Sloan Kettering’s director for cancer vaccines, in a release from the cancer center.

The early dramatic results from mRNA vaccines on cancer could help soften the suspicions some Americans have toward more common vaccines. They also could help restore Americans’ trust in medical science — indeed, in science generally. Medical science has blessed our generation with an abundance of preventive methods — including vaccines — and treatments that enable a far greater percentage of us to live longer and healthier lives than our forebears.

We should be grateful.

_____


©2026 Chicago Tribune. Visit at chicagotribune.com. Distributed by Tribune Content Agency, LLC.

 

Comments

blog comments powered by Disqus

 

Related Channels

The ACLU

ACLU

By The ACLU
Amy Goodman

Amy Goodman

By Amy Goodman
Armstrong Williams

Armstrong Williams

By Armstrong Williams
Austin Bay

Austin Bay

By Austin Bay
Ben Shapiro

Ben Shapiro

By Ben Shapiro
Betsy McCaughey

Betsy McCaughey

By Betsy McCaughey
Bill Press

Bill Press

By Bill Press
Bonnie Jean Feldkamp

Bonnie Jean Feldkamp

By Bonnie Jean Feldkamp
Cal Thomas

Cal Thomas

By Cal Thomas
Clarence Page

Clarence Page

By Clarence Page
Danny Tyree

Danny Tyree

By Danny Tyree
David Harsanyi

David Harsanyi

By David Harsanyi
Debra Saunders

Debra Saunders

By Debra Saunders
Dennis Prager

Dennis Prager

By Dennis Prager
Dick Polman

Dick Polman

By Dick Polman
Erick Erickson

Erick Erickson

By Erick Erickson
Froma Harrop

Froma Harrop

By Froma Harrop
Jacob Sullum

Jacob Sullum

By Jacob Sullum
Jamie Stiehm

Jamie Stiehm

By Jamie Stiehm
Jeff Robbins

Jeff Robbins

By Jeff Robbins
Jessica Johnson

Jessica Johnson

By Jessica Johnson
Jim Hightower

Jim Hightower

By Jim Hightower
Joe Conason

Joe Conason

By Joe Conason
John Stossel

John Stossel

By John Stossel
Josh Hammer

Josh Hammer

By Josh Hammer
Judge Andrew P. Napolitano

Judge Andrew Napolitano

By Judge Andrew P. Napolitano
Laura Hollis

Laura Hollis

By Laura Hollis
Marc Munroe Dion

Marc Munroe Dion

By Marc Munroe Dion
Michael Barone

Michael Barone

By Michael Barone
Mona Charen

Mona Charen

By Mona Charen
Rachel Marsden

Rachel Marsden

By Rachel Marsden
Rich Lowry

Rich Lowry

By Rich Lowry
Robert B. Reich

Robert B. Reich

By Robert B. Reich
Ruben Navarrett Jr.

Ruben Navarrett Jr

By Ruben Navarrett Jr.
Ruth Marcus

Ruth Marcus

By Ruth Marcus
S.E. Cupp

S.E. Cupp

By S.E. Cupp
Salena Zito

Salena Zito

By Salena Zito
Star Parker

Star Parker

By Star Parker
Stephen Moore

Stephen Moore

By Stephen Moore
Susan Estrich

Susan Estrich

By Susan Estrich
Ted Rall

Ted Rall

By Ted Rall
Terence P. Jeffrey

Terence P. Jeffrey

By Terence P. Jeffrey
Tim Graham

Tim Graham

By Tim Graham
Tom Purcell

Tom Purcell

By Tom Purcell
Veronique de Rugy

Veronique de Rugy

By Veronique de Rugy
Victor Joecks

Victor Joecks

By Victor Joecks
Wayne Allyn Root

Wayne Allyn Root

By Wayne Allyn Root

Comics

Jeff Danziger Phil Hands Gary McCoy Steve Kelley Mike Beckom Lisa Benson