John Ross Bowie has teased more Big Bang Theory cameos in Stuart Fails To Save The Universe.

The 55-year-old actor has reprised his role as Barry Kripke in the wild sci-fi spinoff series, which also sees Kevin Sussman (Stuart Bloom), Brian Posehn (Bert Kibbler) and Denise (Lauren Lapkus) return for a post apocalyptic comedy.

John was asked why the show works so well with these characters, rather than others like Janine Davis (Regina King), Mary Cooper (Zoe Perry) and Leslie Winkle (Sara Gilbert).

He told TV Insider: "There's something very liberating about this particular set of skills working together that I think people will enjoy.

"Also, I mean, the proof is in the pudding.

"We had a lot of fun working together, and not that anyone you just mentioned wouldn't have been a total blast to work with as well… and I can't say who or who isn't coming back."

John praised the way the characters share such great "chemistry", comparing them to Marvel's X-Men.

He quipped: "I think the chemistry of these four characters and their diverse skill sets [make it work].

"Kevin and Lauren are the big comic book nerds; Bert's specialty is geology; Kripke is physics. It's sort of the X-Men for f**k-ups."

John also reflected on how Stuart Fails The Universe goes beyond the typical time travel and multiverse stories told by the likes of Marvel and DC.

He explained: "It's found its own niche in that it is really absurdistly funny. And not that I mean, the Marvel films and the DC films take great pains. There's always good jokes in those.

"But we are a much more joke-forward show, you know? Chuck Lorre and Bill Prady are writing for us. I think the idea of it being a multi-dimensional road trip is really fun.

"I think there's something about parallel universe tourism that is really exciting right now. And I think our own timeline is so complicated right now that there might be a thirst in America and elsewhere for people to check out other timelines and see how they're going."

The logline for the show reads: "Comic book store owner Stuart Bloom is tasked with restoring reality after he breaks a device built by Sheldon and Leonard, accidentally bringing about a multiverse Armageddon.

"Stuart is aided in this quest by his girlfriend Denise, geologist friend Bert, and quantum physicist/all-around pain in the a** Barry Kripke.

"Along the way, they meet alternate-universe versions of characters we've come to know and love from The Big Bang Theory. As the title implies, things don't go well."