A stroke drug invented at The Scripps Research Institute has shown signs of safety and efficacy in a mid-stage clinical trial. If it succeeds, it would not only help stroke patients, but bring more money to TSRI's top-rated biomedical research.
The drug is designed to improve the usefulness of tPA, a popular stroke drug. Called 3K3A-APC, the ...Read more
RALEIGH, N.C. -- A national organization for conservative millennials is launching a digital ad campaign opposing financial incentives in North Carolina and the other 19 U.S. states that are finalists to land Amazon's second headquarters.
Generation Opportunity advocates for free markets and economic policies that benefit their membership of 18...Read more
SEATTLE -- It's not just housing prices: Seattle is not the bargain it used to be for companies, either.
Historically, the city was a cheaper place to rent office space than a lot of other cities with advanced economies. That held true through last decade's economic upswing, and during the recession.
But the city's recent boom driven by Amazon...Read more
"You might already know this ...," Central Valley farmer Sarah Woolf offered politely, before launching on a primer on California's convoluted water system.
"No, I don't," Sonny Perdue, Trump's secretary of Agriculture, interrupted. "I need all the education I can get."
Nervous laughter filled the Harris-Woolf California Almonds processing ...Read more
BALTIMORE -- Jalina Thompson hardly noticed the two customers who walked into her Metro PCS store in Northeast Baltimore in January with their hoods pulled tight. Temperatures in the city had been frigid for days.
Then one of the men placed a gun on the counter and demanded cash.
"This is real," he said. "I need you to move fast."
While the ...Read more
CHICAGO -- Uptake Technologies is bringing in a former General Electric executive to serve as president of the data analytics startup.
Ganesh Bell, who served as chief digital officer at GE Power, starts in his new role at Uptake on Monday, spokeswoman Abby Hunt said. Bell will report to CEO and co-founder Brad Keywell and will be responsible ...Read more
WASHINGTON -- The White House signaled President Donald Trump will pay close attention to the fate of workers left behind by globalization as a new benchmark for negotiating trade deals around the world.
While trade may be good for America, it hasn't necessarily helped all Americans, the White House Council of Economic Advisers said Wednesday ...Read more
Sinclair Broadcast Group plans to sell Chicago's WGN-TV and stations in New York and nine smaller markets to win federal approval of its proposed $3.9 billion takeover of Tribune Media.
The Hunt Valley, Md.-based broadcaster outlined steps it will take to comply with national TV station ownership rules in a plan filed Wednesday with the Federal...Read more
DETROIT -- Raj Nair, one of the first promotions made by new Ford CEO Jim Hackett, left the company Wednesday afternoon, effective immediately, amid an admission of "inappropriate behavior."
"I sincerely regret that there have been instances where I have not exhibited leadership behaviors consistent with the principles that the company and I ...Read more
WASHINGTON -- Some Federal Reserve policymakers raised concerns last month about the potential for higher inflation and financial instability because of stronger economic growth triggered by the recently enacted tax cuts, according to an account of the meeting released on Wednesday.
Early signs that the effects of the tax cuts "might be ...Read more
With free birthday breakfast meals and all-you-can-eat riblets, the IHOP and Applebee's restaurant chains became a traditional stop for millions of American families seeking a feast.
But casual dining restaurants began to lose their appeal for millennial-generation foodies, and in 2016, Applebee's tried to update its image. The restaurant got ...Read more
LOS ANGELES -- First, Uber framed itself as an alternative to taxis. Now the San Francisco ride-hailing company is rolling out a new service that sounds kind of like a bus.
The ride-hailing company is introducing Express Pool to several cities this week. It's a lower-cost service for passengers who are willing to share rides with strangers and ...Read more
WASHINGTON -- The Supreme Court sharply limited the legal protections for corporate whistleblowers on Wednesday, ruling they are not shielded from being fired under a federal law unless they have reported a potential fraud to the Securities and Exchange Commission.
The justices conceded their ruling might "gut" the whistleblower protections ...Read more
MINNEAPOLIS -- 3M Co. has agreed to give the state of Minnesota $850 million to resolve the biggest environmental lawsuit in the state's history over the decades-long contamination of groundwater in the east metro area.
On Tuesday, the day that the trial between the state and 3M was set to begin, Attorney General Lori Swanson said the money ...Read more
SAN DIEGO -- Broadcom trimmed its hostile takeover offer for Qualcomm on Wednesday in the wake of the San Diego company agreeing to pay more for Dutch automotive chip maker NXP Semiconductors.
But Broadcom said it remains committed to acquiring Qualcomm even with NXP in tow.
Broadcom's new offer is $79 per share -- $57 in cash and $22 in ...Read more
Facebook's head of advertising, Rob Goldman, has apologized after a tweetstorm that seemed to downplay Russian interference in U.S. elections on the heels of indictments made by special counsel Robert Mueller late last week.
Goldman, who the company said was acting on his own and not on behalf of Facebook, tweeted Friday, "I have seen all of ...Read more
A federal judge has handed IMDb a victory in its ongoing feud with the state of California and SAG-AFTRA over whether the Amazon-owned website can publish the ages of actors.
Judge Vince Chhabria of the Northern District of California ruled in his decision Tuesday that California cannot enforce a law that would compel IMDb to remove the age of ...Read more
A team of investors is expected to meet with the New York attorney general's office as soon as Wednesday in a move to salvage their proposed purchase of the beleaguered Weinstein Co.'s assets, according to people familiar with the matter.
Former U.S. Small Business Administration head Maria Contreras-Sweet and Southern California billionaire ...Read more
The sleek aircraft, really more rocket than plane, dropped from the wing of a B-52 before shooting through the sky above Point Mugu Sea Range off the California coast, leaving a long, white contrail in its wake.
The unmanned X-51A hit Mach 4.8, almost five times the speed of sound, with help from a solid rocket booster. Then the Boeing Co. ...Read more
CHAPEL HILL, N.C. -- Negotiations to form one of the nation's largest health care companies in North Carolina are snagged on a sensitive issue: Who will control the joint organization overseeing some 60 hospitals and 90,000 employees.
UNC Health Care CEO William Roper provided an update Tuesday after discussing the matter in a closed session ...Read more
- Applebee's and IHOP's new recipe for success: technology, takeout and takeovers
- White House signals new trade deals must help those left behind
- Sinclair Broadcast will sell WGN-TV, New York station in bid to buy Tribune Media
- Agriculture Secretary Sonny Perdue gets grounded in California
- Uber introduces Express Pool service, which sounds kind of like a bus