What's the link between PCOS/PMOS and dementia?
Up to 6 million women in the U.S. have PMOS. That's what used to be called polycystic ovary syndrome and now is named polyendocrine metabolic ovarian syndrome. The name change happened because it turns out that PMOS isn't simply a condition characterized by hormone fluctuations that trigger irregular menstrual periods, excess hair growth, acne and infertility. Its health effects are also caused by fluctuations in hormones that impact weight, metabolic and mental health, skin, and the reproductive system. Recognizing this has beneficially shifted how the disease is diagnosed and treated and how we understand its repercussions on a wide range of bodily systems, including the brain.
For example, a study in the Journal of the Endocrine Society proposes a new way of addressing PMOS's increased risk for dementia by evaluating a woman's insulin resistance, diabetes, obesity, and chronic inflammation. These are health problems associated with PMOS and medical science now suggests they're linked to the increased risk for Alzheimer's disease and other forms of dementia.
That's why we are stressing the importance of achieving metabolic health through nutrition, exercise, weight management, control of blood glucose levels, improved gut health, better sleep quality and stress management to reduce the risk of PMOS-associated dementia. Bonus: GLP-1s seem to work magic on correcting this condition.
If you're contending with irregular periods, mood swings and metabolic problems like high blood sugar or obesity, see a gynecologist for evaluation and help improving your metabolic profile; ask your doc about a GLP-1; and join me in the AI coaching program at 4YOUngevity.com.
Health pioneer Michael Roizen, M.D., is chief wellness officer emeritus at the Cleveland Clinic and author of four No. 1 New York Times bestsellers. Check out his latest, "The Great Age Reboot: Cracking the Longevity Code for a Younger Tomorrow," and find out more at www.4YOUngevity.com. Email your health and wellness questions to Dr. Mike at drmikerealage@gmail.com.
(c)2026 Michael Roizen, M.D.
Distributed by King Features Syndicate, Inc.
(c) 2026 Michael Roizen, M.D. Distributed by King Features Syndicate, Inc.
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