NEW ORLEANS AT BUFFALO
Obvious starters: Michael Thomas (Saints), Mark Ingram (Saints), Alvin Kamara (Saints), LeSean McCoy (Bills).
Who to start: Dual-threat quarterback Tyrod Taylor (Bills) has built one of the highest fantasy floors for his position. If Charles Clay (Bills) is active, you're starting him unless you have an elite option.
Who to sit: Buffalo has only allowed multiple touchdown passes once this season, and Drew Brees (Saints) traditionally produces below his normal standards away from home. Ted Ginn Jr. (Saints) is a boom-or-bust option for Week 10. In five career games against New Orleans, Kelvin Benjamin (Bills) has been held to three or fewer receptions four times and only scored one touchdown.
Sleeper: Benjamin's presence could take the pressure off of Jordan Matthews (Bills).
GREEN BAY AT CHICAGO
Obvious starters: Jordan Howard (Bears).
Who to start: There has been steady improvement for Brett Hundley (Packers) since he was thrust into action. Solid production with his legs makes him a solid streaming option. Aaron Jones (Packers) has RB2 upside facing a Chicago defense that has allowed a rushing touchdown in six of eight games this season. Both Davante Adams (Packers) and Randall Cobb (Packers) deserve flex consideration after catching seven and five balls respectively, last week. I expect Chicago to get Tarik Cohen (Bears) more involved in the offense coming off its bye week, providing solid flex potential.
Who to sit: Former elite option Jordy Nelson (Packers) has only five receptions for 48 yards in Hundley's two starts.
Sleeper: The Bears D/ST is a sneaky streaming option at home against an offense in flux.
CLEVELAND AT DETROIT
Obvious starters: Matthew Stafford (Lions), Lions D/ST, Golden Tate (Lions), Marvin Jones (Lions).
Who to start: Pass-specialist Duke Johnson (Browns) still deserves respect in PPR leagues regardless of playing for a subpar offense in general. Theo Riddick (Lions) continues to be a solid flex option in PPR leagues. Cleveland is terrible covering the tight end position so there's potential in streaming both Eric Ebron (Lions) and Darren Fells (Lions) if you're desperate.
Who to sit: Inefficient running back Isaiah Crowell (Browns) is a risky flex play at best. DeShone Kizer (Browns) hasn't thrown a touchdown pass in 105 pass attempts. Like Crowell, Ameer Abdullah (Lions) should be more productive with the amount of touches he receives.
Sleeper: Rookie tight end David Njoku (Browns) is a streaming option in deeper leagues facing a Detroit defense allowing close to 60 receiving yards per game to the position.
CINCINNATI AT TENNESSEE
Obvious starters: A.J. Green (Bengals), Joe Mixon (Bengals), DeMarco Murray (Titans), Delanie Walker (Titans).
Who to start: Since Week 4, tight end Tyler Kroft (Bengals) leads Cincinnati in receptions. Both Rishard Matthews (Titans) and Corey Davis (Titans) are low-end flex options against a pretty solid pass defense.
Who to sit: Inconsistent QB Andy Dalton (Bengals) has failed to 140 passing yards in two of the past three games. Marcus Mariota (Titans) is a risky start considering the lack of running production since he hurt his hamstring. Derrick Henry (Titans) is touchdown dependent with Murray still playing such a significant role in the offense. Eric Decker (Titans) no longer has fantasy value with Davis back.
Sleeper: The Titans D/ST are a solid streaming option considering Cincinnati's penchant for turnovers.
PITTSBURGH AT INDIANAPOLIS
Obvious starters: Le'Veon Bell (Steelers), Antonio Brown (Steelers), Steelers D/ST, Jack Doyle (Colts), T.Y. Hilton (Colts).
Who to start: The matchup is too good to sit Ben Roethlisberger (Steelers) even if he is away from home. JuJu Smith-Schuster (Steelers) continues to be a high-end flex option with WR2 upside.
Who to sit: It will take more than Martavis Bryant (Steelers) being active to trust him in fantasy going forward. Despite the usage, Frank Gore (Colts) on has only two touchdowns this season -- the last one coming Week 3.
Sleeper: Rookie running back Marlon Mack (Colts) is clearly the more dynamic option in the Indy backfield. He's a flex play in the deepest leagues.
N.Y. JETS AT TAMPA BAY
Obvious starters: Bilal Powell (Jets), Austin Seferian-Jenkins (Jets), DeSean Jackson (Buccaneers), Doug Martin (Buccaneers), Cameron Brate (Buccaneers).
Who to start: Thanks to the matchup, Josh McCown (Jets) continues to be one of the safest streaming options at quarterback. Robby Anderson (Jets) officially has WR2 upside going forward. Elijah McGuire (Jets) will be worthy of flex consideration if Matt Forte misses this game. Ryan Fitzpatrick (Buccaneers) is a priority streaming option against a New York defense that has allowed multiple touchdown passes in seven of nine games this season.
Who to sit: Forte (Jets) -- fresh off a two TD performance -- is dealing with swelling in his surgically repaired knee and hasn't practiced as of Wednesday. Jermaine Kearse (Jets) only has five receptions over the last three games.
Sleeper: Rookie wide receiver Chris Godwin (Buccaneers) will have an expanded role with Mike Evans serving a one-game suspension.
MINNESOTA AT WASHINGTON
Obvious starters: Stefon Diggs (Vikings), Adam Thielen (Vikings), Kyle Rudolph (Vikings), Vikings D/ST.
Who to start: Jerick McKinnon (Vikings) is an RB2 with RB1 upside because of his breakaway ability. Vernon Davis (Redskins) is a borderline TE1 with at least 58 receiving yards in five of the last six games. Chris Thompson (Redskins) continues to be a RB2 with RB1 upside in PPR, especially if Jamison Crowder misses more time with a hamstring injury.
Who to sit: Case Keenum (Vikings) won't have much room for error with Teddy Bridgewater ready to return. You would think Latavius Murray (Vikings) would be useful with the usage he's receiving -- he has one big game in the last four -- but I consider him a desperation play at this point. Minnesota hasn't allowed more than 209 passing yards or multiple touchdown passes since Week 3, making Kirk Cousins (Redskins) a risky start this week. Tight end Jordan Reed (Redskins) has had one good game this entire season while dealing with some sort of ailment each week. I would consider Josh Doctson (Redskins) a flex play if he wasn't facing shutdown corner Xavier Rhodes.
Sleeper: Rob Kelley (Redskins) has only surpassed 30 rushing yards once this season, but he does have three touchdowns in the past two weeks.
L.A. CHARGERS AT JACKSONVILLE
Obvious starters: Melvin Gordon (Chargers), Leonard Fournette (Jaguars), Jaguars D/ST.
Who to start: Even as Jacksonville's leading receiver, Marqise Lee (Jaguars) is still only worthy of flex consideration in PPR leagues.
Who to sit: Stay away from Los Angeles' passing game this week, including Philip Rivers (Chargers) and Keenan Allen (Chargers) -- although Allen's value could be saved by a heavy volume of targets.
Sleeper: Jacksonville's only weakness through the air is against tight ends, putting Hunter Henry (Chargers) in the TE1 conversation.
HOUSTON AT L.A. RAMS
Obvious starters: DeAndre Hopkins (Texans), Lamar Miller (Texans), Todd Gurley (Rams), Rams D/ST.
Who to start: Jared Goff (Rams) proved last week he could shred a secondary in disarray. Cooper Kupp (Rams) and Robert Woods (Rams) remain solid flex plays in PPR with WR2 upside.
Who to sit: Tom Savage (Texans) isn't worth your time, unless you want to spend it being upset he can't utilize the skill-set of Will Fuller (Texans). Even against a struggling secondary, Sammy Watkins (Rams) remains a touchdown dependent option.
Sleeper: Tight end C.J. Fiedorowicz (Texans) should be activated this week off the injured reserve.
DALLAS AT ATLANTA
Obvious starters: Dak Prescott (Cowboys), Matt Ryan (Falcons), Devonta Freeman (Falcons), Tevin Coleman (Falcons).
Who to start: Wide receivers Terrance Williams (Cowboys) and Cole Beasley (Cowboys) both deserve flex consideration and have WR2 upside if Dez Bryant (Cowboys) is significantly limited or out this week. If Julio Jones (Falcons) can play through his ankle pain, he's an obvious start. Mohamed Sanu (Falcons) remains a solid flex play in PPR with WR2 upside if Jones is truly limited or out Sunday. Austin Hooper (Falcons) is a low-end TE1 if Jones and Freeman are limited or out.
Who to sit: The NFL Players Association's emergency injunction request on behalf of running back Ezekiel Elliott (Cowboys) was denied Thursday, meaning he begins his six-game suspension immediately. Bryant is dealing with bruised knee that might keep him sidelined this week. I'd expect him to be limited if he does play. This is a terrible matchup for Jason Witten (Cowboys).
Sleeper: Alfred Morris (Cowboys) has RB2 upside with Elliott sidelined.
N.Y. GIANTS AT SAN FRANCISCO
Obvious starters: Evan Engram (Giants), Carlos Hyde (49ers).
Who to start: San Francisco has allowed multiple touchdown passes in four straight games, making Eli Manning (Giants) a solid streaming option this week. Orleans Darkwa (Giants) has RB2 upside against fantasy's worst run defense. Sterling Shepard (Giants) has WR2 upside because San Francisco's secondary has allowed a wide receiver to score in eight of nine games this season. C.J. Beathard (49ers) is a sneaky streaming option at QB considering the New York secondary has allowed three or more touchdown passes in four of the last five games. Marquise Goodwin (49ers) deserves flex consideration as Beathard's primary target.
Who to sit: It could go either way for the Giants D/ST or 49ers D/ST, but I don't trust either one at this point.
Sleeper: New York's defense has allowed a tight end to score a touchdown in every game this season, so fire up Garrett Celek (49ers) if you're in a pinch at the position.
NEW ENGLAND AT DENVER
Obvious starters: Tom Brady (Patriots), Rob Gronkowski (Patriots), Patriots D/ST.
Who to start: Slot machine Danny Amendola (Patriots) should receive some extra looks with Chris Hogan sidelined. Both running backs James White (Patriots) and Dion Lewis (Patriots) are valuable flex plays in PPR. If Demaryius Thomas (Broncos) and Emmanuel Sanders (Broncos) aren't limited Sunday night, they at least deserve flex consideration, even with Brock Osweiler at quarterback.
Who to sit: I expect Denver's "No Fly Zone" to bounce back from an embarrassing performance last week, meaning Brandin Cooks (Patriots) could have a rough go of it against elite corner Chris Harris Jr. Friends don't let friends start Brock Osweiler (Broncos).
Sleeper: Devontae Booker (Broncos) appears to be the Denver running back you want at the moment. He'll have a decent opportunity to take advantage of a solid matchup on SNF.
MIAMI AT CAROLINA
Obvious starters: Jarvis Landry (Dolphins), Cam Newton (Panthers), Christian McCaffrey (Panthers), Panthers D/ST.
Who to start: A healthy DeVante Parker (Dolphins) has WR2 upside, especially against Carolina's inexperienced group of cornerbacks. The usage Devin Funchess (Panthers) receives supports flex value going forward.
Who to sit: Jay Cutler (Dolphins) can go back to your bench or the waiver wire now that he's gotten that aberration of a performance against Oakland out of the way. Carolina's linebackers should be able to keep Damien Williams (Dolphins) and Kenyan Drake (Dolphins) in check. This is a poor matchup for Jonathan Stewart (Panthers).
Sleeper: Carolina could have rookie wide receiver Curtis Samuel (Panthers) slide into Steve Smith's old role eventually.
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