Health & Spirit

NR supplements help repair your mitochondria

By Michael Roizen, M.D. and Mehmet Oz, M.D. on

The comedian Andy Kaufman used to lip-sync part of the 1950s "Mighty Mouse" cartoon theme song: "Here I come to save the day!" Well, another Mighty Mouse -- several, actually -- recently made their debut in a study published in the journal Nature, titled "Nicotinamide Riboside Preserves Cardiac Function in a Mouse Model of Dilated Cardiomyopathy." One day they might save the day, too, for your heart and brain.

In a recent column, we described how your mitochondria, the power plants in each cell in your body, enable every cell's healthy metabolic activity. If these Mighty Mitos cannot deliver the energy your body needs, various organ systems suffer. Well, it's now known that as we age those Mighty Mitos may not get the support they need to do their job from a coenzyme called nicotinamide adenine dinucleotide, shortened to NAD. But, according to that Nature study, boosting NAD by taking its precursor, nicotinamide riboside (a form of niacin or vitamin B-3) may help re-power the mitochondria and protect aging organs and the brain.

The researchers reported that mice with heart problems have lower NAD levels -- and so do humans with heart diseases. Further, they said that giving mice more nicotinamide riboside improves their heart health, by restoring NAD levels. And even more amazing, once the mice had more fuel for the Mighty Mitos, they became Mightier Mice! Seems the NAD boost also improved memory impairment! Very encouraging. All we can say is that they may "B" on to something that will help give you a mightily younger RealAge!



Mehmet Oz, M.D. is host of "The Dr. Oz Show," and Mike Roizen, M.D. is Chief Wellness Officer and Chair of Wellness Institute at Cleveland Clinic. To live your healthiest, tune into "The Dr. Oz Show" or visit

(c) 2018Michael Roizen, M.D. and Mehmet Oz, M.D.

Distributed by King Features Syndicate, Inc.

(c) 2018 Michael Roizen, M.D. and Mehmet Oz, M.D. Distributed by King Features Syndicate, Inc.

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