Once people are exposed to PFAS, the chemicals remain in their bodies for a long time – months to years, depending on the specific compound – and they can accumulate over time.

Research consistently demonstrates that PFAS are associated with a variety of adverse health effects. A review by a panel of experts looking at research on PFAS toxicity concluded with a high degree of certainty that PFAS contribute to thyroid disease, elevated cholesterol, liver damage, and kidney and testicular cancer.

Further, they concluded with a high degree of certainty that PFAS also affect babies exposed in utero by increasing their likelihood of being born at a lower birth weight and responding less effectively to vaccines, while impairing women’s mammary gland development, which may adversely affect a mom’s ability to breastfeed.

The review also found evidence that PFAS may contribute to a number of other disorders, though further research is needed to confirm existing findings: inflammatory bowel disease, reduced fertility, breast cancer, and an increased likelihood of miscarriage and developing high blood pressure and preeclampsia during pregnancy. Additionally, current research suggests that babies exposed prenatally are at higher risk of experiencing obesity, early-onset puberty and reduced fertility later in life.

Collectively, this is a formidable list of diseases and disorders.

PFAS chemicals have been around since the late 1930s, when a DuPont scientist created one by accident during a lab experiment. DuPont called it Teflon, which eventually became a household name for its use on nonstick pans.

Decades later, in 1998, Scotchgard maker 3M notified the Environmental Protection Agency that a PFAS chemical was showing up in human blood samples. At the time, 3M said low levels of the manufactured chemical had been detected in people’s blood as early as the 1970s.

The Agency for Toxic Substances and Disease Registry has a toxicological profile for PFAS. And the EPA had issued advisories and health-based guidelines. But despite the lengthy list of serious health risks linked to PFAS and a tremendous amount of federal investment in PFAS-related research in recent years, PFAS hadn’t been regulated at the federal level in the United States until now.

The new drinking water standards set limits for five individual PFAS – PFOA, PFOS, PFNA, PFHxS and HFPO-DA – as well as mixtures of these chemicals. The standards are part of the EPA’s road map for PFAS regulations.

The EPA has also proposed listing nine PFAS as hazardous substances under the Resource Conservation and Recovery Act, a move that worries utilities and businesses that use PFAS-containing products or processes because of the expense of cleanup.

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