And the spike is occurring statewide. Orange County confirmed 56 coronavirus-related deaths last week, the highest weekly death toll that the county has reported since the pandemic hit the U.S.
According to the California Department of Public Health, which collects information from each county's distinct tracking methods, the biggest spike in cases and deaths occurred Wednesday, when 733 new cases and 24 deaths were reported.
With the spike in deaths and cases, Newsom announced Monday that Orange County -- which has the third-most cases in the state -- was added to the list of now 19 counties that the state is watching for surges in infection numbers or hospitalization rates.
While Orange County continues to move forward with its expanded reopening, other parts of California are scaling back.
The state on Sunday ordered the closure of bars in seven counties on its watch list -- Los Angeles, Fresno, Kern, San Joaquin, Tulare, Kings and Imperial -- and encouraged the same of eight others -- Contra Costa, Santa Clara, Sacramento, Riverside, Ventura, San Bernardino, Santa Barbara and Stanislaus.
Contra Costa County officials on Monday announced they will further delay reopenings as COVID-19 cases surged past 2,800 infections.
The county previously had cleared bars, personal services not involving close contact with the face, indoor dining, gyms, fitness centers, limited indoor leisure activities, museums and hotels for tourism and individual travel to reopen July 1.
"With the sharp rise in community spread and hospitalizations, it does not make sense at this time to open additional business sectors that could further accelerate community transmission," officials said.
"These businesses and activities will remain closed in Contra Costa until county data indicate that the spread of the virus has slowed, as measured by at least a week of stable case numbers, hospitalizations and% of tests that are positive," the county added in a statement on its public health website."
The seven-day average number of COVID-19 patients in hospitals in the county rose by 75% from June 15 to June 29. The number of residents testing positive for the disease has risen from 38 to 87 a day, with the percentage of positive tests moving from 5% to 6%.