Obvious starters: Marshawn Lynch (Raiders), Michael Crabtree (Raiders), Jared Cook (Raiders), Alex Smith (Chiefs), Travis Kelce (Chiefs), Tyreek Hill (Chiefs).
Who to start: Derek Carr (Raiders) had his best game of the year against the Chiefs Week 7 (417 yards and three TDs). Kareem Hunt (Chiefs) last looked like himself -- he had 117 total yards -- against the Raiders almost two months ago.
Who to sit: Amari Cooper (Raiders) appears to be past a concussion and is now only dealing with a sprained ankle.
Sleeper: Playmaker Cordarrelle Patterson (Raiders) is a solid flex option if Cooper remains limited or out.
DALLAS AT N.Y. GIANTS
Obvious starters: Alfred Morris (Cowboys), Dez Bryant (Cowboys), Evan Engram (Giants), Sterling Shepard (Giants).
Who to start: I expect a "get-right" game from Dak Prescott (Cowboys) with such a favorable match-up. Jason Witten (Cowboys) has averaged five receptions for 53 yards in 29 games against the Giants during his Hall of Fame career. Eli Manning (Giants) returns to face a Cowboys defense that has allowed multiple touchdown passes in nine of 11 games. Orleans Darkwa (Giants) retains his flex value thanks to high usage.
Who to sit: Cole Beasley (Cowboys) isn't even productive enough to recommend in deeper PPR leagues.
Sleeper: Rod Smith (Cowboys) has scored a touchdown in two straight games.
DETROIT AT TAMPA BAY
Obvious starters: Matthew Stafford (Lions), Marvin Jones (Lions), Golden Tate (Lions), Mike Evans (Buccaneers).
Who to start: PPR specialist Theo Riddick (Lions) has upside beyond his normal flex appeal with Abdullah limited. Jameis Winston (Buccaneers) is a solid streaming option considering the Lions defense just allowed Joe Flacco to pass for 269 yards and two TDs. You could do worse than DeSean Jackson (Buccaneers) as a flex play. As long as Winston is quarterback, Cameron Brate (Buccaneers) has fantasy value.
Who to sit: Even if Ameer Abdullah (Lions) plays (neck injury), you can't trust him. The same can be said for Doug Martin (Buccaneers). Peyton Barber (Buccaneers) would be a solid flex candidate if Martin is limited or out.
Sleeper: Rookie wideout Kenny Golladay (Lions) has proven himself a big-time playmaker, opening up potential flex value.
MINNESOTA AT CAROLINA
Obvious starters: Adam Thielen (Vikings), Vikings D/ST, Cam Newton (Panthers), Christian McCaffrey (Panthers).
Who to start: The Panthers have actually allowed 10 touchdown passes in its previous four home games, which bodes well for Case Keenum (Vikings) continuing his solid fantasy production. The floor for Stefon Diggs (Vikings) is PPR flex option. Latavius Murray (Vikings) has at least 15 carries in seven straight games.
Who to sit: Kyle Rudolph (Vikings) could struggle against a defense that has only allowed six receptions to tight ends over the past three games. Jerick McKinnon (Vikings) has definitely become more of a companion piece to Murray. This is a very tough match-up for Greg Olsen (Panthers), whom I still don't believe is 100 percent. I expect Devin Funchess (Panthers) to struggle as well with a potential match-up against Xavier Rhodes.
SAN FRANCISCO AT HOUSTON
Obvious starters: DeAndre Hopkins (Texans), Lamar Miller (Texans).
Who to start: Jimmy Garoppolo (49ers) is a premium streaming option this week. Marquise Goodwin (49ers) has averaged 82 yards per game in the four games since Pierre Garcon was lost for the year and now he has an actual quarterback throwing the ball to him. Stephen Anderson (Texans), a solid streaming option this week, had 79 yards on five receptions (12 targets) and a TD last week after C.J. Fiedorowicz was hurt.
Who to sit: Carlos Hyde (49ers) hasn't scored a touchdown since Week 6. No matter the match-up, it's best to leave Tom Savage (Texans) on the waiver wire.
Sleeper: Consider Trent Taylor (49ers) a flex option in deeper PPR leagues. He's the prototype of a slot receiver -- think Julien Edelman or Danny Amendola -- Garoppolo was used to in New England.
N.Y. JETS AT DENVER
Obvious starters: Robby Anderson (Jets), Austin Seferian-Jenkins (Jets), Demaryius Thomas (Broncos), Emmanuel Sanders (Broncos).
Who to start: Josh McCown (Jets) has proven he's worth the risk of late, especially against a Broncos defense that is clearly a shell of its former self. Matt Forte (Jets) and Bilal Powell (Jets) are decent flex options in deeper leagues.
Who to sit: I'm not anticipating a third straight 100-yard performance for Jermaine Kearse (Jets). Despite the juicy match-up, I can't recommend Trevor Siemian (Broncos). C.J. Anderson (Broncos) has been one of the more inconsistent players at his position this season. You can't trust Devontae Booker (Broncos) either.
Sleeper: The Broncos D/ST may be a shell of its former self, but it's still talented enough to take advantage of this match-up.
TENNESSEE AT ARIZONA
Obvious starters: Delanie Walker (Titans), Larry Fitzgerald (Cardinals).
Who to start: His legs give Marcus Mariota (Titans) a high fantasy floor, making him a premium stream with a decent match-up. Both DeMarco Murray (Titans) and Derrick Henry (Titans) are high-end flex options. Blaine Gabbert (Cardinals) can be streamed if you're desperate as he faces a Titans defense that has allowed four passing touchdowns in three separate games this season. The Titans have also allowed 30 receptions to tight ends over the past five games, making Ricky Seals-Jones (Cardinals) a streaming option in PPR.
Who to sit: I expect Rishard Matthews (Titans) to be limited if he returns from a hamstring injury. Adrian Peterson (Cardinals) has yet to be cleared to play due to a neck injury. It's a tough match-up even if he does play.
Sleeper: Over the past month, rookie receiver Corey Davis (Titans) is second only to Walker in targets.
WASHINGTON AT L.A. CHARGERS
Obvious starters: Samaje Perine (Redskins), Vernon Davis (Redskins), Philip Rivers (Chargers), Melvin Gordon (Chargers), Keenan Allen (Chargers).
Who to start: Jamison Crowder (Redskins) has regained his stature in PPR leagues. Josh Doctson (Redskins) deserves flex consideration due to his red zone prowess.
Who to sit: Lower your expectations for Kirk Cousins (Redskins). The Chargers haven't allowed multiple touchdown passes since Week 5.
Sleeper: It wouldn't surprise me if Hunter Henry (Chargers) was a focal point of the offense against a Redskins defense that has allowed a touchdown to tight ends in seven of the last 10 games.
PHILADELPHIA AT L.A. RAMS
Obvious starters: Carson Wentz (Eagles), Zach Ertz (Eagles), Alshon Jeffery (Eagles), Jared Goff (Rams), Todd Gurley (Rams).
Who to start: Jay Ajayi (Eagles) deserves flex consideration against a Rams defense that struggles against the run. Ajayi has RB2 upside. Nelson Agholor (Eagles) deserves flex consideration in deeper leagues. Sammy Watkins (Rams) has scored a touchdown in four of the last five weeks. Cooper Kupp (Rams) has WR2 upside in PPR leagues.
Who to sit: LeGarrette Blount (Eagles) hasn't scored a touchdown since Ajayi joined the team.
Sleeper: Backup tight end Trey Burton (Eagles) will benefit if Ertz doesn't clear the NFL's concussion protocol.
SEATTLE AT JACKSONVILLE
Obvious starters: Russell Wilson (Seahawks), Jimmy Graham (Seahawks), Seahawks D/ST, Leonard Fournette (Jaguars), Jaguars D/ST.
Who to start: Mike Davis (Seahawks) deserves flex consideration in deeper leagues. J.D. McKissic (Seahawks) has proven capable in deeper PPR leagues. Marqise Lee (Jaguars) maintains his WR2 value in PPR.
Who to sit: Lower your expectations for Doug Baldwin (Seahawks) in such a difficult match-up. The time to stream Blake Bortles (Jaguars) will be the next two weeks, not now.
Sleeper: Former Heisman finalist Dede Westbrook (Jaguars) has received 19 targets over the past two weeks.
BALTIMORE AT PITTSBURGH
Obvious starters: Le'Veon Bell (Steelers), Antonio Brown (Steelers).
Who to start: Alex Collins (Ravens) has four touchdowns in the last three games. Martavis Bryant (Steelers) has flex value with JuJu Smith-Schuster out due to suspension.
Who to sit: Joe Flacco (Ravens) can't be trusted in fantasy. Jeremy Maclin (Ravens) has surpassed 56 receiving yards only once this season and hasn't caught a touchdown since Week 8. Ben Roethlisberger (Steelers) has a tough match-up against a Ravens defense that has only allowed three passing touchdowns in the last six games.
Sleeper: Danny Woodhead (Ravens) has yet to payoff the hype as a high-end flex option, but could be significantly utilized this week.
NEW ENGLAND AT MIAMI
Obvious starters: Tom Brady (Patriots), Dion Lewis (Patriots), Brandin Cooks (Patriots), Patriots D/ST, Jarvis Landry (Dolphins).
Who to start: Kenyan Drake (Dolphins) should pick up where he left off last weekend against a Patriots run defense who have given up a league-worst 4.99 yards per carry this season.
Who to sit: Rex Burkhead (Patriots) has maximized his opportunities over the last month. His production can't continue at this pace. Dwayne Allen (Patriots) failed to catch a pass the last time Rob Gronkowski missed a game. Danny Amendola (Patriots) only had one catch for 15 yards two weeks ago against the Dolphins. I simply don't trust Jay Cutler (Dolphins) week-to-week and neither should you. DeVante Parker (Dolphins) has two receptions for 10 yards the past two games.
Sleeper: We could see the return of Chris Hogan (Patriots), which could offset the loss of Gronkowski this week.
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