Obvious starters: LeSean McCoy (Bills), A.J. Green (Bengals).
Who to start: Tyrod Taylor (Bills) makes a solid streaming option thanks to the high floor he produces each week. Charles Clay (Bills) has been a top-five fantasy tight end since Week 12 last season, but you should temper your expectations against a Bengals defense that has been very tough on the position this season. Speaking of, both the Bengals D/ST and Bills D/ST deserve streaming consideration this week.
Who to sit: Rookie wide receiver Zay Jones (Bills) should see more targets with Jordan Matthews out, but he's still behind McCoy and Clay on a team that doesn't pass that much anyways. Andy Dalton (Bengals) has looked significantly better the past two weeks, but this is a really tough matchup. Rookie running back Joe Mixon (Bengals) will eventually turn his usage into production, and fulfill his potential as a flex option. Tyler Kroft (Bengals) has earned streaming consideration at tight end the past two weeks, but faces a stingy Buffalo secondary.
Sleeper: PPR specialist Giovani Bernard (Bengals) has shown a knack for big plays so far.
N.Y. JETS AT CLEVELAND
Obvious starters: None.
Who to start: Bilal Powell (Jets) is a RB2 if turf toe keeps Matt Forte sidelined again. The Cleveland defense has given up multiple touchdowns or over 100 yards in three of four games to tight ends this season, making Austin Seferian-Jenkins (Jets) a borderline TE1 this week. This is the week Isaiah Crowell (Browns) might actually return value for those brave souls who drafted him as a RB2. Duke Johnson (Browns) has actually led Cleveland in targets, receptions and yards the past two games, supporting his RB2 upside in PPR leagues.
Who to sit: Elijah McGuire (Jets) deserves to be stashed in your league after last week's production, but he's a ways away from earning a spot in your lineup. Consistency has alluded Jermaine Kearse (Jets) and Robby Anderson (Jets) so far, which means I'd keep them benched or on the waiver wire unless you are absolutely desperate at your flex position.
Sleeper: Cleveland's offensive line has yet to prove it can protect rookie quarterback DeShone Kizer, who is getting sacked and pressured at an alarming rate. The Jets D/ST could surprise as a streaming option this week.
CAROLINA AT DETROIT