BOSTON -- The Detroit Tigers capitalized with the bases loaded in the sixth inning to take a 2-1 lead.
The Red Sox loaded the bases in the seventh inning and delivered the knockout blow to end the Tigers' season.
Shane Victorino hit a grand slam off Jose Veras over the Green Monster.
That turned a 2-1 deficit for the Red Sox into a 5-2 lead.
The Tigers went on to lose by that margin in Game 6 of the American League Championship Series late Saturday night.
The Red Sox and St. Louis Cardinals will play in the World Series.
Jonny Gomes led off the seventh with a double off the left field wall. Max Scherzer got Stephen Drew to strike out on a 94 m.p.h. fastball, but gave up a walk to rookie Xander Bogaerts.
Drew Smyly was brought in to pitch to Jacoby Ellsbury. A fielding error by shortstop Jose Iglesias on a ground ball by Ellsbury loaded the bases. Veras was brought in to pitch to Victorino and gave up the grand slam on a breaking ball.
"We got Victorino out a lot on breaking pitches," said catcher Alex Avila. "He hadn't done anything -- I think he had one hit off a breaking ball all series. We struck him out a lot with it. We got to 0-2 quickly with him and tried to make another good pitch with the breaking ball to where you would get the strikeout. You're talking about a matter of an inch or two and getting a swing and a miss or him hitting it the way he did. A little bit up than what we wanted it to be."
Scherzer allowed four hits, five walks, three runs (two earned) over 6 1/3 innings with eight strikeouts.
Scherzer had escaped a major jam in the bottom of sixth inning.
Scherzer hit Victorino with a pitch, then gave up a walk to Pedroia. Pitching coach Jeff Jones came out to talk to Scherzer with David Ortiz due up.
Smyly had been warming up, but Leyland left Scherzer in to pitch to Ortiz.
Don Kelly, who had entered as a pinch-runner for Jhonny Peralta in the top of the sixth, caught a fly ball hit to left by Ortiz.
On a 1-1 count against Mike Napoli, Scherzer threw a wild pitch, moving the runners to second and third with one out.
Napoli struck out swinging at a changeup and Jarrod Saltalamacchia popped out to short.
"They were patient," Scherzer said. "They hit a couple mistakes. I got away with a couple mistakes. I thought I pitched well, but not well enough."
The Tigers had taken a 2-1 lead in the top of the sixth. Torii Hunter led off with a walk and Miguel Cabrera followed with a single to left. That ended the night for Red Sox starter Clay Buchholtz.
Lefty Franklin Morales was brought in to pitch to Prince Fielder, but threw four straight balls to load the bases with none out.
Morales stayed in to pitch to Victor Martinez. On a 2-1 count, Martinez hit a ball off the Green Monster for a two-run single.
The Tigers had a chance to break the game open at that point, but didn't.
Righty Brandon Workman came in to pitch to Jhonny Peralta. Peralta hit a grounder to second. Pedroia tagged Martinez, then threw home and caught Prince Fielder halfway home. Jarrod Saltalamacchia was able to tag Fielder, who fell down short of third base, for the double play. Alex Avila was called out on strikes.
"Well, both teams played good all series," said Tigers manager Jim Leyland. "We had a couple of blunders tonight, but it was a tough series.
"I want to congratulate the Boston Red Sox, John Farrell, Ben Cherington, the players. They deserve to win. They beat us. And I wish them the best. They played very well and there was a lot of good games.
"Like I said, collectively, start with me, the coaches, the players, we just didn't do quite enough."
Buchholz allowed four hits, two walks and two earned runs over five-plus innings with four strikeouts for the Red Sox.
The Red Sox had just taken a 1-0 lead in the bottom of the fifth. With two outs,
Bogaerts doubled off the wall in left-center. Jacoby Ellsbury followed with a line drive RBI single to right, giving the Red Sox a 1-0 lead.
The Tigers had a baserunner in four of the first five innings, but had no runs to show for it.
Leyland said Buchholz has tipped his hand in the media, saying he would take a page out of Jon Lackey's book.
"I thought Buchholz used his curveball," Leyland said. "He tipped his hand actually in the paper today, he said he took a page out of Lackey's book and was going to use his curve a little more, and he sure did. It didn't surprise us. And we got him out of there pretty early.
"The difference really, when you look at the series, is they hit a couple of big bombs and we just didn't quite do that. They hit a couple of timely, two or three really timely home runs. Big Papi and tonight Victorino."
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